S59I (p.Ser59Ile) variant of IL18R1 (Interleukin-18 receptor 1)
S59I (p.Ser59Ile) in IL18R1 (Interleukin-18 receptor 1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
S59I (p.Ser59Ile) variant details
- p.Ser59Ile
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.0603
- REVEL 0.02
- CADD 6.99
- PolyPhen-2 0.23
- SIFT 0.11
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available