S24L (p.Ser24Leu) variant of IL18R1 (Interleukin-18 receptor 1)
S24L (p.Ser24Leu) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
S24L (p.Ser24Leu) variant details
- p.Ser24Leu
- cosmic curated COSV10509
- Missense
- Variant Prioritization Score for Impact Estimate 0.0594
- REVEL 0.01
- CADD 6.58
- PolyPhen-2 0.01
- SIFT 0.67
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available