S21Y (p.Ser21Tyr) variant of IL18R1 (Interleukin-18 receptor 1)
S21Y (p.Ser21Tyr) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data and structural context.
S21Y (p.Ser21Tyr) variant details
- p.Ser21Tyr
- TOPMed rs1442467116
- gnomAD rs1442467116
- Missense
- Variant Prioritization Score for Impact Estimate 0.0351
- REVEL 0.02
- CADD 0.14
- PolyPhen-2 0.11
- SIFT 0.06
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available