R25H (p.Arg25His) variant of IL18R1 (Interleukin-18 receptor 1)
R25H (p.Arg25His) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
R25H (p.Arg25His) variant details
- p.Arg25His
- cosmic curated COSV52122
- ExAC rs764661915
- gnomAD rs764661915
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.19
- CADD 24.20
- PolyPhen-2 0.98
- SIFT 0.02
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available