P35S (p.Pro35Ser) variant of IL18R1 (Interleukin-18 receptor 1)
P35S (p.Pro35Ser) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
P35S (p.Pro35Ser) variant details
- p.Pro35Ser
- TOPMed rs1319638276
- gnomAD rs1319638276
- Missense
- Variant Prioritization Score for Impact Estimate 0.257
- REVEL 0.18
- CADD 20.90
- PolyPhen-2 0.78
- SIFT 0.30
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available