P35R (p.Pro35Arg) variant of IL18R1 (Interleukin-18 receptor 1)
P35R (p.Pro35Arg) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
P35R (p.Pro35Arg) variant details
- p.Pro35Arg
- TOPMed rs774529728
- gnomAD rs774529728
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.30
- CADD 22.40
- PolyPhen-2 0.84
- SIFT 0.08
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available