P35L (p.Pro35Leu) variant of IL18R1 (Interleukin-18 receptor 1)
P35L (p.Pro35Leu) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
P35L (p.Pro35Leu) variant details
- p.Pro35Leu
- TOPMed rs774529728
- gnomAD rs774529728
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.22
- CADD 22.00
- PolyPhen-2 0.57
- SIFT 0.34
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available