L8M (p.Leu8Met) variant of IL18R1 (Interleukin-18 receptor 1)
L8M (p.Leu8Met) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
L8M (p.Leu8Met) variant details
- p.Leu8Met
- ExAC rs754624008
- TOPMed rs754624008
- gnomAD rs754624008
- Missense
- Variant Prioritization Score for Impact Estimate 0.0858
- REVEL 0.08
- CADD 5.69
- PolyPhen-2 0.06
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available