L6S (p.Leu6Ser) variant of IL18R1 (Interleukin-18 receptor 1)
L6S (p.Leu6Ser) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
L6S (p.Leu6Ser) variant details
- p.Leu6Ser
- gnomAD 2-102362677-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.282
- REVEL 0.23
- MetaLR 0.02
- MetaSVM -1.03
- CADD 21.20
- PolyPhen-2 0.60
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available