L38M (p.Leu38Met) variant of IL18R1 (Interleukin-18 receptor 1)
L38M (p.Leu38Met) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
L38M (p.Leu38Met) variant details
- p.Leu38Met
- gnomAD 2-102367878-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- REVEL 0.35
- MetaLR 0.33
- MetaSVM -0.63
- CADD 23.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available