L10H (p.Leu10His) variant of IL18R1 (Interleukin-18 receptor 1)
L10H (p.Leu10His) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
L10H (p.Leu10His) variant details
- p.Leu10His
- gnomAD 2-102362689-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.20
- MetaLR 0.03
- MetaSVM -0.98
- CADD 22.40
- PolyPhen-2 0.82
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available