K54T (p.Lys54Thr) variant of IL18R1 (Interleukin-18 receptor 1)
K54T (p.Lys54Thr) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
K54T (p.Lys54Thr) variant details
- p.Lys54Thr
- gnomAD 2-102367927-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0653
- REVEL 0.02
- MetaLR 0.05
- MetaSVM -1.03
- CADD 0.14
- PolyPhen-2 0.00
- SIFT 0.24
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available