K39N (p.Lys39Asn) variant of IL18R1 (Interleukin-18 receptor 1)
K39N (p.Lys39Asn) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
K39N (p.Lys39Asn) variant details
- p.Lys39Asn
- gnomAD 2-102367883-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.145
- REVEL 0.07
- MetaLR 0.01
- MetaSVM -1.12
- CADD 16.00
- PolyPhen-2 0.52
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available