H65Y (p.His65Tyr) variant of IL18R1 (Interleukin-18 receptor 1)
H65Y (p.His65Tyr) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
H65Y (p.His65Tyr) variant details
- p.His65Tyr
- gnomAD 2-102367959-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.118
- REVEL 0.10
- MetaLR 0.03
- MetaSVM -0.95
- CADD 3.08
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available
- Literature evidence available