H40Y (p.His40Tyr) variant of IL18R1 (Interleukin-18 receptor 1)
H40Y (p.His40Tyr) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
H40Y (p.His40Tyr) variant details
- p.His40Tyr
- ExAC rs763710435
- gnomAD rs763710435
- Missense
- Variant Prioritization Score for Impact Estimate 0.107
- REVEL 0.08
- CADD 0.16
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available