H27Y (p.His27Tyr) variant of IL18R1 (Interleukin-18 receptor 1)
H27Y (p.His27Tyr) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
H27Y (p.His27Tyr) variant details
- p.His27Tyr
- gnomAD 2-102367845-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0756
- REVEL 0.03
- MetaLR 0.06
- MetaSVM -1.00
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available