H27P (p.His27Pro) variant of IL18R1 (Interleukin-18 receptor 1)
H27P (p.His27Pro) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
H27P (p.His27Pro) variant details
- p.His27Pro
- gnomAD 2-102367846-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.106
- REVEL 0.08
- MetaLR 0.09
- MetaSVM -0.87
- CADD 2.86
- PolyPhen-2 0.09
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available