G33E (p.Gly33Glu) variant of IL18R1 (Interleukin-18 receptor 1)
G33E (p.Gly33Glu) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
G33E (p.Gly33Glu) variant details
- p.Gly33Glu
- gnomAD 2-102367864-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.436
- REVEL 0.38
- MetaLR 0.32
- MetaSVM -0.36
- CADD 25.40
- PolyPhen-2 1.00
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available