E64K (p.Glu64Lys) variant of IL18R1 (Interleukin-18 receptor 1)
E64K (p.Glu64Lys) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
E64K (p.Glu64Lys) variant details
- p.Glu64Lys
- ExAC rs776795173
- gnomAD rs776795173
- Missense
- Variant Prioritization Score for Impact Estimate 0.107
- REVEL 0.04
- CADD 4.23
- PolyPhen-2 0.00
- SIFT 0.82
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available