E34D (p.Glu34Asp) variant of IL18R1 (Interleukin-18 receptor 1)
E34D (p.Glu34Asp) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
E34D (p.Glu34Asp) variant details
- p.Glu34Asp
- gnomAD rs1438663084
- Missense
- Variant Prioritization Score for Impact Estimate 0.228
- REVEL 0.21
- CADD 22.80
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available