C43F (p.Cys43Phe) variant of IL18R1 (Interleukin-18 receptor 1)
C43F (p.Cys43Phe) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
C43F (p.Cys43Phe) variant details
- p.Cys43Phe
- gnomAD 2-102367894-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.104
- REVEL 0.08
- MetaLR 0.14
- MetaSVM -1.02
- CADD 0.07
- PolyPhen-2 0.00
- SIFT 0.78
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available