C3Y (p.Cys3Tyr) variant of IL18R1 (Interleukin-18 receptor 1)
C3Y (p.Cys3Tyr) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data, published literature, and structural context.
C3Y (p.Cys3Tyr) variant details
- p.Cys3Tyr
- gnomAD 2-102362668-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.065
- REVEL 0.01
- MetaLR 0.00
- MetaSVM -0.95
- CADD 0.01
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Middle Eastern population (allele frequency 0.00052)
- Structural context available
- Literature evidence available