C3G (p.Cys3Gly) variant of IL18R1 (Interleukin-18 receptor 1)
C3G (p.Cys3Gly) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data and structural context.
C3G (p.Cys3Gly) variant details
- p.Cys3Gly
- TOPMed rs1678645488
- Missense
- Variant Prioritization Score for Impact Estimate 0.0361
- REVEL 0.02
- CADD 0.05
- PolyPhen-2 0.01
- SIFT 0.33
- Most common in the Latino/Admixed American population (allele frequency 2.4e-05)
- Structural context available