C22Y (p.Cys22Tyr) variant of IL18R1 (Interleukin-18 receptor 1)
C22Y (p.Cys22Tyr) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
C22Y (p.Cys22Tyr) variant details
- p.Cys22Tyr
- gnomAD rs763304570
- Missense
- Variant Prioritization Score for Impact Estimate 0.426
- REVEL 0.30
- CADD 23.80
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available