C22R (p.Cys22Arg) variant of IL18R1 (Interleukin-18 receptor 1)
C22R (p.Cys22Arg) in IL18R1 (Interleukin-18 receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
C22R (p.Cys22Arg) variant details
- p.Cys22Arg
- gnomAD 2-102367830-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.419
- REVEL 0.34
- MetaLR 0.02
- MetaSVM -1.11
- CADD 24.70
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available
- Literature evidence available