Y88C (p.Tyr88Cys) variant of IL18 (Interleukin-18)
Y88C (p.Tyr88Cys) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
Y88C (p.Tyr88Cys) variant details
- p.Tyr88Cys
- gnomAD 11-112148700-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.491
- REVEL 0.47
- MetaLR 0.16
- MetaSVM -0.81
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available