Y37N (p.Tyr37Asn) variant of IL18 (Interleukin-18)
Y37N (p.Tyr37Asn) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
Y37N (p.Tyr37Asn) variant details
- p.Tyr37Asn
- gnomAD 11-112150189-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0942
- REVEL 0.07
- MetaLR 0.06
- MetaSVM -0.97
- CADD 1.25
- PolyPhen-2 0.00
- SIFT 0.28
- Most common in the African/African-American population (allele frequency 3.1e-05)
- Structural context available
- Literature evidence available