Y24H (p.Tyr24His) variant of IL18 (Interleukin-18)
Y24H (p.Tyr24His) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
Y24H (p.Tyr24His) variant details
- p.Tyr24His
- gnomAD rs1455115453
- Missense
- Variant Prioritization Score for Impact Estimate 0.476
- REVEL 0.41
- MetaLR 0.36
- MetaSVM -0.13
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available