V55I (p.Val55Ile) variant of IL18 (Interleukin-18)
V55I (p.Val55Ile) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
V55I (p.Val55Ile) variant details
- p.Val55Ile
- TOPMed rs1438010700
- Missense
- Variant Prioritization Score for Impact Estimate 0.325
- REVEL 0.18
- MetaLR 0.27
- MetaSVM -0.64
- CADD 23.80
- PolyPhen-2 0.99
- SIFT 0.03
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available