T81S (p.Thr81Ser) variant of IL18 (Interleukin-18)
T81S (p.Thr81Ser) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
T81S (p.Thr81Ser) variant details
- p.Thr81Ser
- gnomAD 11-112148722-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.16
- MetaLR 0.11
- MetaSVM -1.02
- CADD 19.00
- PolyPhen-2 0.99
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available