T70S (p.Thr70Ser) variant of IL18 (Interleukin-18)
T70S (p.Thr70Ser) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
T70S (p.Thr70Ser) variant details
- p.Thr70Ser
- gnomAD rs1199026248
- Missense
- Variant Prioritization Score for Impact Estimate 0.1
- REVEL 0.06
- MetaLR 0.08
- MetaSVM -1.02
- CADD 3.37
- PolyPhen-2 0.04
- SIFT 0.61
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available