T22R (p.Thr22Arg) variant of IL18 (Interleukin-18)
T22R (p.Thr22Arg) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
T22R (p.Thr22Arg) variant details
- p.Thr22Arg
- 1000Genomes rs61734549
- ESP rs61734549
- ExAC rs61734549
- TOPMed rs61734549
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- REVEL 0.17
- MetaLR 0.16
- MetaSVM -0.96
- CADD 21.40
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available