S86N (p.Ser86Asn) variant of IL18 (Interleukin-18)
S86N (p.Ser86Asn) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
S86N (p.Ser86Asn) variant details
- p.Ser86Asn
- ExAC rs780531931
- TOPMed rs780531931
- gnomAD rs780531931
- Missense
- Variant Prioritization Score for Impact Estimate 0.0724
- REVEL 0.04
- MetaLR 0.03
- MetaSVM -0.99
- CADD 0.02
- PolyPhen-2 0.00
- SIFT 0.28
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available