S72F (p.Ser72Phe) variant of IL18 (Interleukin-18)
S72F (p.Ser72Phe) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
S72F (p.Ser72Phe) variant details
- p.Ser72Phe
- Ensembl rs2135313477
- Missense
- Variant Prioritization Score for Impact Estimate 0.251
- REVEL 0.03
- MetaLR 0.21
- MetaSVM -0.99
- CADD 16.30
- SIFT 0.11
- Most common in the HGDP:DRUZE population (allele frequency 0.014)
- Structural context available