S72C (p.Ser72Cys) variant of IL18 (Interleukin-18)
S72C (p.Ser72Cys) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
S72C (p.Ser72Cys) variant details
- p.Ser72Cys
- gnomAD 11-112150083-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.04
- MetaLR 0.21
- MetaSVM -0.99
- CADD 16.50
- PolyPhen-2 0.80
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available