S43C (p.Ser43Cys) variant of IL18 (Interleukin-18)
S43C (p.Ser43Cys) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
S43C (p.Ser43Cys) variant details
- p.Ser43Cys
- gnomAD 11-112150170-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0686
- REVEL 0.02
- MetaLR 0.07
- MetaSVM -1.02
- CADD 1.49
- PolyPhen-2 0.00
- SIFT 0.20
- Population evidence available
- Structural context available
- Literature evidence available