R63G (p.Arg63Gly) variant of IL18 (Interleukin-18)
R63G (p.Arg63Gly) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
R63G (p.Arg63Gly) variant details
- p.Arg63Gly
- ESP rs199733090
- ExAC rs199733090
- TOPMed rs199733090
- gnomAD rs199733090
- Missense
- Variant Prioritization Score for Impact Estimate 0.142
- REVEL 0.15
- MetaLR 0.06
- MetaSVM -1.03
- CADD 3.65
- PolyPhen-2 0.01
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available