P79L (p.Pro79Leu) variant of IL18 (Interleukin-18)
P79L (p.Pro79Leu) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
P79L (p.Pro79Leu) variant details
- p.Pro79Leu
- gnomAD rs1174079432
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.07
- MetaLR 0.07
- MetaSVM -1.08
- CADD 17.60
- PolyPhen-2 0.70
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available