P64S (p.Pro64Ser) variant of IL18 (Interleukin-18)
P64S (p.Pro64Ser) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
P64S (p.Pro64Ser) variant details
- p.Pro64Ser
- gnomAD rs1329702763
- Missense
- Variant Prioritization Score for Impact Estimate 0.313
- REVEL 0.05
- MetaLR 0.24
- MetaSVM -0.79
- CADD 13.70
- PolyPhen-2 0.66
- SIFT 0.06
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available