P5A (p.Pro5Ala) variant of IL18 (Interleukin-18)
P5A (p.Pro5Ala) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
P5A (p.Pro5Ala) variant details
- p.Pro5Ala
- ExAC rs774621216
- gnomAD rs774621216
- Missense
- Variant Prioritization Score for Impact Estimate 0.115
- REVEL 0.05
- MetaLR 0.09
- MetaSVM -1.01
- CADD 0.04
- PolyPhen-2 0.02
- SIFT 0.50
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available