L41F (p.Leu41Phe) variant of IL18 (Interleukin-18)
L41F (p.Leu41Phe) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
L41F (p.Leu41Phe) variant details
- p.Leu41Phe
- gnomAD 11-112150177-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.07
- MetaLR 0.13
- MetaSVM -1.00
- CADD 9.04
- PolyPhen-2 0.60
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available