L33M (p.Leu33Met) variant of IL18 (Interleukin-18)
L33M (p.Leu33Met) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
L33M (p.Leu33Met) variant details
- p.Leu33Met
- gnomAD 11-112150201-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.24
- MetaLR 0.25
- MetaSVM -0.66
- CADD 23.90
- PolyPhen-2 1.00
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available