K40T (p.Lys40Thr) variant of IL18 (Interleukin-18)
K40T (p.Lys40Thr) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
K40T (p.Lys40Thr) variant details
- p.Lys40Thr
- gnomAD 11-112150179-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.186
- REVEL 0.14
- MetaLR 0.19
- MetaSVM -0.76
- CADD 14.10
- PolyPhen-2 0.71
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available