K40E (p.Lys40Glu) variant of IL18 (Interleukin-18)
K40E (p.Lys40Glu) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
K40E (p.Lys40Glu) variant details
- p.Lys40Glu
- gnomAD 11-112150180-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.17
- REVEL 0.07
- MetaLR 0.11
- MetaSVM -1.01
- CADD 15.50
- PolyPhen-2 0.20
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available