K17Q (p.Lys17Gln) variant of IL18 (Interleukin-18)
K17Q (p.Lys17Gln) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
K17Q (p.Lys17Gln) variant details
- p.Lys17Gln
- gnomAD rs1317762487
- Missense
- Variant Prioritization Score for Impact Estimate 0.129
- REVEL 0.07
- MetaLR 0.12
- MetaSVM -1.00
- CADD 13.40
- PolyPhen-2 0.01
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available