I84T (p.Ile84Thr) variant of IL18 (Interleukin-18)
I84T (p.Ile84Thr) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
I84T (p.Ile84Thr) variant details
- p.Ile84Thr
- gnomAD 11-112148712-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.29
- MetaLR 0.07
- MetaSVM -1.04
- CADD 14.70
- PolyPhen-2 0.91
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available