I48V (p.Ile48Val) variant of IL18 (Interleukin-18)
I48V (p.Ile48Val) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
I48V (p.Ile48Val) variant details
- p.Ile48Val
- gnomAD 11-112150156-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- REVEL 0.14
- MetaLR 0.12
- MetaSVM -0.92
- CADD 15.20
- PolyPhen-2 0.01
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available