I48T (p.Ile48Thr) variant of IL18 (Interleukin-18)
I48T (p.Ile48Thr) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
I48T (p.Ile48Thr) variant details
- p.Ile48Thr
- gnomAD 11-112150155-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.578
- REVEL 0.70
- MetaLR 0.24
- MetaSVM -0.33
- CADD 24.10
- PolyPhen-2 0.94
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available