I26M (p.Ile26Met) variant of IL18 (Interleukin-18)
I26M (p.Ile26Met) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
I26M (p.Ile26Met) variant details
- p.Ile26Met
- gnomAD rs1381138292
- Missense
- Variant Prioritization Score for Impact Estimate 0.171
- REVEL 0.05
- MetaLR 0.08
- MetaSVM -1.03
- CADD 19.50
- PolyPhen-2 0.37
- SIFT 0.11
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available