I19V (p.Ile19Val) variant of IL18 (Interleukin-18)
I19V (p.Ile19Val) in IL18 (Interleukin-18) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
I19V (p.Ile19Val) variant details
- p.Ile19Val
- ExAC rs766654584
- gnomAD rs766654584
- Missense
- Variant Prioritization Score for Impact Estimate 0.14
- REVEL 0.03
- MetaLR 0.07
- MetaSVM -1.01
- CADD 14.90
- PolyPhen-2 0.01
- SIFT 0.20
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available